（英文原文）RelationshipBetweenAlcoholConsumptionandCardiacStructureandFunctionintheElderly

Background—Excessivealcoholconsumptionisassociatedwithcardiomyopathy,buttheinfluenceofmoderatealcoholuseoncardiacstructureandfunctionislargelyunknown.

MethodsandResults—Westudiedparticipantsfromvisit5oftheAtherosclerosisRiskinCommunities(ARIC)study(76±5yearsand60%women)whounderwenttransthoracicechocardiography,excludingformerdrinkersandthosewithsignificantvalvulardisease.Participantswereclassifiedinto4categoriesbasedonself-reportedalcoholintake:nondrinkers,drinkersof≤7,≥7to14,and≥14drinksperweek.Werelatedalcoholintaketomeasuresofcardiacstructureandfunction,stratifiedbysex,andfullyadjustedforcovariates.Inbothgenders,increasingalcoholintakewasassociatedwithlargerleftventriculardiastolicandsystolicdiametersandlargerleftatrialdiameter(P0.05).Inmen,increasingalcoholintakewasassociatedwithgreaterleftventricularmass(8.2±3.8gperconsumptioncategory;P=0.)andhigherE/E′ratio(0.82±0.33perconsumptioncategory;P=0.).Inwomen,increasingalcoholintakewasassociatedwithlowerleftventricularejectionfraction(?1.9±0.6%perconsumptioncategory;P=0.)andatendencyforworseleftventriculargloballongitudinalstrain(0.45±0.25%perconsumptioncategory;P=0.07).

Conclusions—Inanelderly







































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